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high yield and reliable post-translational modifications.

In the rapidly advancing field of biotechnology and life sciences, producing complex recombinant proteins efficiently and at scale remains a major challenge. While bacterial systems like E. coli offer fast growth and simple handling, they often fall short when expressing eukaryotic proteins that require proper folding and post-translational modifications. This is where yeast expressionespecially using Pichia pastoris, shines.

At Gene Universal, we offer a specialized Pichia pastoris Expression Service that brings unmatched flexibility and performance to protein production. Whether you are working on enzymes, therapeutic proteins, or monoclonal antibodies, our yeast expression platform is designed to meet your unique needs with precision and scalability.

Why Pichia pastoris?

Pichia pastoris is a methylotrophic yeast that combines the best of both microbial and eukaryotic expression systems. It grows to high cell densities in simple media and can secrete recombinant proteins directly into the culture medium, simplifying downstream processing. More importantly, it supports authentic folding and glycosylation, making it suitable for expressing biologically active proteins that bacteria cannot handle.

A Streamlined Workflow Built for Results

Gene Universal’s service begins with codon optimization, ensuring your gene is tuned for optimal expression in the yeast system. We then move through gene synthesis and subcloning, all the way to fermentation, expression, and purification. Our proprietary fermentation technology is designed to maximize yield while maintaining consistency, even for challenging protein targets.

In the final stages, proteins are purified using our state-of-the-art AKTA purifier system, equipped with multiple column types including ion exchange, hydrophobic interaction, molecular sieves, and affinity columns. This guarantees high-purity protein output, ready for downstream research or application.

Applications Across Industries

Our yeast expression system has been used in projects spanning biopharmaceutical development, diagnostic kit manufacturing, vaccine research, industrial enzyme production, and academic studies. Its high expression level, scalability, and eukaryotic processing capabilities make it an ideal choice for virtually any protein expression project.

Elevate your protein research with Gene Universal’s expert yeast expression solutions. Contact us to explore how Pichia pastoris can power your next discovery.

http://www.geneuniversal.com
Gene Universal

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